Society of Toxicology: Safety Assessment of an Intramedullary Bone Stabilization Device Using a Light-Curable Monomer

Zani BG, Baird R, Stanley JRL, Markham PM, Wilke M, Zeiter S, Beck A, Nehrbass, Kopia GA, Edelman ER, Rabiner R. ‘Safety Assessment of an Intramedullary Bone Stabilization Device Using a Light-Curable Monomer.’

Summary: Traditional methods of bone fixation (e.g., metal rods and screws) are not effective for osteoporotic patients. A device for percutaneous bone stabilization utilizing a light-curable polymer system that conforms to each patient’s unique intramedullary (IM) canal has been developed. We evaluated local and systemic biocompatibility of a photodynamic balloon stabilization system (PBSS) cured in situ in sheep. Results show that IM application of a light curable PBSS is a safe, feasible method for IM fixation.

Poster presented at: Society of Toxicology (SOT); 2016 Mar 13-17; New Orleans, LA.