Vascular Medicine: Leukocyte recruitment and expression of chemokines following different forms of vascular injury

Welt FG, Tso C, Edelman ER, Kjelsberg MA, Paolini JF, Seifert P, Rogers C. Leukocyte recruitment and expression of chemokines following different forms of vascular injury. Summary: Inflammation plays a central role in restenosis following coronary intervention. Recent human and animal data suggest important differences between the inflammatory responses to simple balloon angioplasty compared with […]

Journal of Vascular Research: Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig

Nugent HM, Groothuis A, Seifert P, Guerraro JL, Nedelman M, Mohanakumar T, Edelman ER. Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. Summary: Vascular access complications are a major problem in hemodialysis patients. Native arteriovenous fistulae, historically the preferred mode ofaccess, have a patency […]

Biophys J: Reaction diffusion model of the enzymatic erosion of insoluble fibrillar matrices

Tzafriri, A.R., M. Bercovier, and H. Parnas. Reaction diffusion model of the enzymatic erosion of insoluble fibrillar matrices. Summary: Predicting the time course of in vivo biodegradation is a key issue in the design of an increasing number of biomedical applications such as sutures, tissue analogs and drug-delivery devices. The design of such biodegradable devices is […]

Circulation Research: Arterial ultrastructure influences transport of locally delivered drugs

Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs. Summary: An incomplete understanding of the transport forces and local tissue structures that modulate drug distribution has hampered local pharmacotherapies in many organ systems. These issues are especially relevant to arteries, where stent-based delivery allows fine control of locally directed drug release. Circulation Research. 2002 […]

J Pharm Sci: Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxel

Lovich MA, Creel CJ, Hong K, Hwang CW, Edelman ER. Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxel. J Pharm Sci. 2001 Sep. 90(9): 1324-1335.

Circulation: Physiological transport forces govern drug distribution for stent-based delivery

Hwang CW, Wu D, Edelman ER. Physiological transport forces govern drug distribution for stent-based delivery. Circulation. 2001 Jul 31. 104(5): 600-605.

JACC: Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months

Drachman DE, Edelman ER, Seifert P, Groothuis AR, Bornstein DA, Kamath KR, Palasis M, Yang D, Nott SH, Rogers C. Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months. JACC. 2000 Dec;36(7): 2325-2332.

Biomaterials: Correlation of transarterial transport of various dextrans with their physicochemical properties

Elmalak O, Lovich MA, Edelman E. Correlation of transarterial transport of various dextrans with their physicochemical properties. Biomaterials. 2000 Nov; 21(22): 2263-2272.

Journal of Surgical Research: Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis

Tavakkolizadeh A, Shen R, Abraham P, Kormi N, Seifert P, Edelman ER, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis. Journal of Surgical Research. 2000 Jun; 91(1): 77-82.

Circulation Research: Arterial paclitaxel distribution and deposition

Creel CJ, Lovich MA, Edelman ER. Arterial paclitaxel distribution and deposition. Circulation Research. 2000 Apr;86(8):879-884.