K Nakamura, MD; JH Keating, DVM; ER Edelman, MD, PhD. Pathology of Endovascular Stents. Summary: Coronary artery disease (CAD) represents the leading cause of death worldwide, attributed to more than 17.5 million deaths annually, accounting for approximately 1 of every 3 deaths. In the United States, contemporary decreases in CAD-related mortality correlate with the 2 decades after the Surgeon General report […]
Tag Archives: JK
Sci Transl Med: Arterial microanatomy determines the success of energy-based renal denervation in controlling hypertension
Tzafriri AR, Keating JH, Markham PM, Spognardi AM, L Stanley JR, Wong G, Zani BG, Highsmith D, O’Fallon P, Fuimaono K, Mahfoud F, Edelman ER. Arterial microanatomy determines the success of energy-based renal denervation in controlling hypertension. Summary: Renal denervation (RDN) is a treatment option for patients with hypertension resistant to conventional therapy. Clinical trials […]
J Am Coll Cardiol: Innervation patterns may limit response to endovascular renal denervation
Tzafriri AR, Mahfoud F, Keating JH, Markham PM, Spognardi A, Wong G, Fuimaono K, Böhm M, Edelman ER. Innervation patterns may limit response to endovascular renal denervation. Summary: The purpose of this study was to correlate response to endovascular radiofrequency ablation of renal arteries with nerve and ganglia distributions. We examined how renal neural network anatomy affected […]
JACC Cardiovasc Interv: Methodological Standardization for the Pre-Clinical Evaluation of Renal Sympathetic Denervation
Sakakura K, Ladich E, Edelman ER, Markham P, Stanley JR, Keating J, Kolodgie FD, Virmani R, Joner M..Methodological Standardization for the Pre-Clinical Evaluation of Renal Sympathetic Denervation. Summary: Transcatheter ablation of renal autonomic nerves is a viable option for the treatment of resistant arterial hypertension; however, structured pre-clinical evaluation with standardization of analytical procedures remains a […]