Press Release: Study Validates New Approach for Optimizing Endovascular Drug Delivery Using Stents with a Deployable Coating That Enhances Sirolimus Distribution Compared to Traditional DES

“Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings” published online in Journal of Controlled Release “This preclinical demonstration of the enhanced and more uniform drug and biomarker distribution by stents with deployable coatings could lead to more rapid and improved healing after stent implantation,” said David Kandzari, M.D., Director […]

Press Release: Preclinical safety studies must include equally balanced male/female animal models to shed light on sex-dependent vascular responses in humans

“Sex Differences in the Outcomes of Stent Implantation in Mini-Swine Model” published in PLOS ONE “Retrospective analyses of pooled animal data can provide important insights into sex-dependent anatomic and pathophysiologic differences,” said Rami Tzafriri, PhD, Director of Research and Innovation, CBSET. LEXINGTON, Mass., Feb. 12, 2018 – CBSET, a non-for-profit preclinical research institute dedicated to […]

Press Release: CILcare’s age-related hearing loss model enriched with NAC as positive control

Preclinical data to be presented at annual mid-winter meeting of the Association of Research in Otolaryngology (ARO) LEXINGTON, Mass., Feb. 8, 2018 – CILcare Inc.,the world’s leading CRO specializing in hearing therapies, will present preclinical data at the upcoming “ARO 14th Annual Mid-Winter Meeting” in San Diego validating the effect of NAC natural active ingredient in […]

Journal of Controlled Release: Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings

Tzafriri AR, Garcia-Polite F, Li X, Keating J, Balaguer JM, Zani B, Bailey L, Markham P, Kiorpes TC, Carlyle W, Edelman ER. Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings. Summary: Innovations in drug eluting stent designs make it increasingly important to develop models for differentiating performance through spatial […]

PLoS One: Sex differences in the outcomes of stent implantation in mini-swine model

Kunio M, Wong G, Markham PM, Edelman ER. Sex differences in the outcomes of stent implantation in mini-swine model. Summary: Sex-related differences have been noted in cardiovascular anatomy, pathophysiology, and treatment responses, yet we continued to drive evaluation of vascular device development in animal models without consideration of animal sex. We aimed to understand sex-related […]

EuroPCR 2018, May 22-25, 2018, Paris, France

Join CBSET at EuroPCR 2018, May 16-19, 2018, at the Palais de Congres, Paris, France, the official annual meeting of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) and the world-leading Course in Interventional Cardiovascular Medicine, bringing together 12,000+ participants every year. CBSET’s Director of Research and Innovation, Rami Tzafriri, PhD, will be presenting during two sessions: […]

MassBio – Convergence of Medical Devices & Drugs, May 3, Waltham, MA

Join CBSET at the second annual MassBio Medical Device Event, “The Convergence of Medical Devices & Drugs: Advances in Drug Delivery”, which will be held on May 3, 2018 12:00 PM – 5:30 PM, at the Westin Waltham, 70 3rd Avenue, Waltham, MA. MassBio’s second annual Medical Device Event will continue the vital conversation around the […]

Sensors, Biomarkers, and Devices in Medicine: Symposium Plus, Apr 24, 2018, Boston, MA

Join CBSET at Sensors, Biomarkers, and Devices in Medicine: Symposium Plus Apr 24, 2018, at Tufts University School of Dental Medicine, Room 1414 (1 Kneeland Street, Boston), from 9:00 am – 3:00 pm. CBSET executives attending the meeting will include John Keating, Director of Pathology, Michael Naimark, Director of Business Development, Rami Tzafriri, Director of Research and Innovation, and Misty […]

GTC 15th Annual Stem Cell Summit, April 12–13, 2018, Boston, MA

Join CBSET at the GTC 15th Annual Stem Cell Summit, April 12–13, 2018, in Boston, MA. The Stem Cell Summit provides information on cutting-edge developments in all areas of stem cell research from bench to bedside, including the biology, medicine, applications, regulations, product development, and the commercialization of stem cells. This summit comprises of presentations, […]