Biophys J: Reaction diffusion model of the enzymatic erosion of insoluble fibrillar matrices

Tzafriri, A.R., M. Bercovier, and H. Parnas. Reaction diffusion model of the enzymatic erosion of insoluble fibrillar matrices. Summary: Predicting the time course of in vivo biodegradation is a key issue in the design of an increasing number of biomedical applications such as sutures, tissue analogs and drug-delivery devices. The design of such biodegradable devices is […]

Circulation Research: Arterial ultrastructure influences transport of locally delivered drugs

Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs. Summary: An incomplete understanding of the transport forces and local tissue structures that modulate drug distribution has hampered local pharmacotherapies in many organ systems. These issues are especially relevant to arteries, where stent-based delivery allows fine control of locally directed drug release. Circulation Research. 2002 […]

J Pharm Sci: Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxel

Lovich MA, Creel CJ, Hong K, Hwang CW, Edelman ER. Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxel. J Pharm Sci. 2001 Sep. 90(9): 1324-1335.

Circulation: Physiological transport forces govern drug distribution for stent-based delivery

Hwang CW, Wu D, Edelman ER. Physiological transport forces govern drug distribution for stent-based delivery. Circulation. 2001 Jul 31. 104(5): 600-605.

JACC: Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months

Drachman DE, Edelman ER, Seifert P, Groothuis AR, Bornstein DA, Kamath KR, Palasis M, Yang D, Nott SH, Rogers C. Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months. JACC. 2000 Dec;36(7): 2325-2332.

Biomaterials: Correlation of transarterial transport of various dextrans with their physicochemical properties

Elmalak O, Lovich MA, Edelman E. Correlation of transarterial transport of various dextrans with their physicochemical properties. Biomaterials. 2000 Nov; 21(22): 2263-2272.

Journal of Surgical Research: Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis

Tavakkolizadeh A, Shen R, Abraham P, Kormi N, Seifert P, Edelman ER, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis. Journal of Surgical Research. 2000 Jun; 91(1): 77-82.

Circulation Research: Arterial paclitaxel distribution and deposition

Creel CJ, Lovich MA, Edelman ER. Arterial paclitaxel distribution and deposition. Circulation Research. 2000 Apr;86(8):879-884.

Circulation: Stent and artery geometry determine intimal thickening independent of arterial injury

Garasic JM, Edelman ER, Squire JC, Seifert P, Williams MS, Rogers C. Stent and artery geometry determine intimal thickening independent of arterial injury. Circulation. 2000 Feb;101(7): 812-8.

Journal of Clinical Investigation. Decreased neointimal formation in Mac-1(-/-) mice reveals a role for inflammation in vascular repair after angioplasty

Simon DI, Dhen Z, Seifert P, Edelman ER, Ballantyne CM, Rogers C. Decreased neointimal formation in Mac-1(-/-) mice reveals a role for inflammation in vascular repair after angioplasty. Journal of Clinical Investigation. 2000 Feb;105(3): 293-300.