Journal of Controlled Release: Luminal flow patterns dictate arterial drug deposition in stent-based delivery

Kolachalama VB, Tzafriri AR, Arifin DY, Edelman ER. Luminal flow patterns dictate arterial drug deposition in stent-based delivery.

Summary: Endovascular stents reside in a dynamic flow environment and yet the impact of flow on arterial drug deposition after stent-based delivery is only now emerging. We employed computational fluid dynamic modeling tools to investigate the influence of luminal flow patterns on arterial drug deposition and distribution.

Journal of Controlled Release 2009 Jan; 133(1):24-30.

January 5, 2009