TCT 2013: Electrode irrigation alters RF ablation treatment zone geometry and preserves medial and adventitial tissue while maintaining injury to renal nerves

Keating J, Markham M, Stanley J, Tzafriri AR, Wong G, Spognardi AM, Fuimaono K, Grunewald D, O’Fallon P, Edelman ER. ‘Electrode irrigation alters RF ablation treatment zone geometry and preserves medial and adventitial tissue while maintaining injury to renal nerves.’ Podium presentation at: Transcatheter Cardiovascular Therapeutics (TCT); 2013 Oct 28-Nov 1; Washington, DC. Summary: We quantitatively […]

Boston AF Symposium: Microbubble and Emboli Production from Left Atrial Ablation with an RF Mesh Ablation System vs. Irrigated Tip Ablation: Outcomes of an Extracorporeal Loop Swine Model

David E. Haines, MD, FHRS; Charles Haffajee, MD, FHRS; Michael V. Orlov, MD, FACC; James R.L. Stanley, DVM, MS, DACVP; Rose Baird, MS; Julie Broderick, MSc; Claire Williams, MA; Ding He, MD, FHRS. ‘Microbubble and Emboli Production from Left Atrial Ablation with an RF Mesh Ablation System vs. Irrigated Tip Ablation: Outcomes of an Extracorporeal […]

TRENDS: Systematic Optimization of Targeted Renal Denervation Therapies Using the Porcine Model: Integration of quantitative biomarker analysis, computer modeling, and histopathologic techniques

Keating JH, Wong G, Tzafriri AR, Zani BG, Baird R, Spognardi AM, Bailey L, LeBrun T, Stanley JRL, Markham PM. ‘Systematic Optimization of Targeted Renal Denervation Therapies Using the Porcine Model: Integration of quantitative biomarker analysis, computer modeling, and histopathologic techniques.’ Presented at: TRENDS, Frankfurt, Germany, 2013

TCT 2012: Stents with absorbable tissue-deployable coatings can distribute drug more uniformly between struts

Tzafriri AR, Bailey L, Stanley JRL, Zani BG, Markham PM, Carlyle WC, McClain JB, Edelman, ER. ‘Stents with absorbable tissue-deployable coatings can distribute drug more uniformly between struts.’ Summary: We examined whether deployment of coating from drug-eluting stents (DES) into surrounding neointima could protect a crystalline drug load from luminal washout and distribute drug more efficiently […]

TCT 2012: A Novel Bioactive and Coating-Free Stent Surface Exhibits a Reduction in Neointimal Hyperplasia by Decreasing Platelet Aggregation and Promoting Endothelialization

Bailey L, Groothius A, Zucker A, Buzzi S, Mader A, Ziogas A, Milleret V, Ehrbar M, Edelman ER. ‘A Novel Bioactive and Coating-Free Stent Surface Exhibits a Reduction in Neointimal Hyperplasia by Decreasing Platelet Aggregation and Promoting Endothelialization.’ TCT-637. JACC. 2012, 60(17_S):. doi:10.1016/j.jacc.2012.08.674.