S Ewen; C Ukena; T Luscher; M Bergmann; P Blankestijn; B Cremers; E Blessing; O Doerr; H Nef; M Schlaich; F Sharif; MVoskuil; T Zeller; AR Tzafriri; E Edelman; Ml Boehm; FMahfoud. Anatomical and procedural determinants of catheter-based renal denervation

Summary: Catheter-based renal sympathetic denervation (RDN) can reduce blood pressure (BP) and sympathetic activity in certain patients with uncontrolled hypertension. Less is known about the impact of renal anatomy and procedural parameters on subsequent BP response. A total of 564 patients with resistant hypertension underwent bilateral RDN using a mono-electrode radiofrequency (RF) catheter (Symplicity Flex, Medtronic). The diameter of renal arteries correlated with SBP change after RDN at 6-month follow-up. Change of SBP was not related to the lengths of the renal artery, presence of ARA, RAD, or the number of RF ablations delivered by a mono-electrode catheter.

Cardiovasc Revasc Med. 2016 Oct – Nov;17(7):474-479. doi: 10.1016/j.carrev.2016.08.004.