Annu Int Conf IEEE Eng Med Biol Soc: Design and implementation of in silico clinical trial for Bioresorbable Vascular Scaffolds

Georgia S Karanasiou, Panagiota I Tsobou, Nikolaos S Tachos, Luca Antonini, Lorenza Petrini, Giancarlo Pennati, Frank Gijsen, Farhad Rikhtegar Nezami, Rami Tzafriri, Ted Vaughan, Martin Fawdry, Dimitrios I Fotiadis. “Design and implementation of in silico clinical trial for Bioresorbable Vascular Scaffolds.”

Summary: In the recent years, Bioresorbable Vascular Scaffolds (BVS) for the treatment of atherosclerosis have been introduced. InSilc is a cloud based in silico clinical trial (ISCT) platform for drug-eluting BVS. The platform integrates multidisciplinary and multiscale models predicting the BVS performance. In this study, we present a use case scenario and demonstrate the functioning of the individual modules and of the whole pipeline and the ability to predict BVS short, medium, long-term outcomes.

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2675-2678. doi: 10.1109/EMBC44109.2020.9176317.