TCT 2015: Enhanced Circumferential Ablation using a Multi-electrode Bipolar/Unipolar Over-the-Wire Renal Denervation RF Catheter System with Closed Loop Sensing

Tzafriri AR; Bailey L; Keating JH; Garcia-Polite F; Markham PM; Prutchi D; Edelman ER. ‘Enhanced Circumferential Ablation using a Multi-electrode Bipolar/Unipolar Over-the-Wire Renal Denervation RF Catheter System with Closed Loop Sensing.’

Summary: Posthoc analysis of SYMPLICITY HTN-3 has revealed a trend for greater blood pressure reductions with increasing number of ablations and highlighted the difficulty of achieving uniform and circumferential ablation pattern using single electrode renal denervation catheters. We examined whether iterative low power multielectrode bipolar-unipolar treatments based on local closed-loop temperature sensing can provide effective four quadrant ablations.

Podium presentation at: Transcatheter Cardiovascular Therapeutics (TCT); Oct 11-14; San Francisco, CA.

TCT-84. J Am Coll Cardiol. 2015;66(15_S):. doi:10.1016/j.jacc.2015.08.128