TCT 2011: Serial Evaluation of the Vascular Response After Implantation Of a New Sirolimus-Eluting Stent with Bioabsorbable Polymer (MiStent® DES) – an Optical Coherence Tomography and Histopathological Study

Attizzani GF, Bezzerra HG, Chamie D, Fujino Y, Spognardi AM, Stanley JRL, Yamamoto H, Mehanna E, Wang W, Carlyle WC, McClain JB, Costa MA.’Serial Evaluation of the Vascular Response After Implantation Of a New Sirolimus-Eluting Stent with Bioabsorbable Polymer (MiStent® DES) – an Optical Coherence Tomography and Histopathological Study.’

Summary: Novel vascular scaffolds aim at equipoise between safety and efficacy. Intravascular optical coherence tomography (OCT) allows in-vivo serial assessment of stent-vessel interactions with high resolution and frequent sampling and may complement histology assessment. We investigated the vascular response to a novel absorbable coating sirolimus-eluting stent (AC-SES) by means of serial OCT and histology evaluation in a porcine model.

Transcatheter Cardiovascular Therapeutics, San Francisco, CA, 2011.