Proc Natl Acad Sci U S A: Tissue engineered endothelial and epithelial implants differentially and synergistically regulate airway repair

Zani BG, Kojima K, Vacanti CA, and Edelman ER. Tissue engineered endothelial and epithelial implants differentially and synergistically regulate airway repair.

Summary: The trilaminate vascular architecture provides biochemical regulation and mechanical integrity. Yet regulatory control can be regained after injury without recapitulating tertiary structure. Tissue-engineered (TE) endothelium controls repair even when placed in the perivascular space of injured vessels.

Proc Natl Acad Sci U S A 2008 May 13; 105(19): 7046-7051.