Tzafriri, AR, Stanley, JR. ‘Embolization of Hydrophilic Coating from Catheters: Can Animal Models Predict Clinical Risk?’

Summary: Medical catheters permit minimally invasive external access for monitoring, imaging, sampling and local delivery of therapeutic agents, and placement of devices like endovascular stents, aneurysm coils and transcatheter valves. To improve ease of manipulation and deliverability the exterior surfaces catheters and sheaths are often coated with lubricious hydrophilic materials, typically composed of synthetic polymers,1-2 such as polyvinylpyrolidone (PVP), polyacrylamide and polyethylene oxide.

Biomaterials Forum. 20153, Q3:23-25