Digestive Diseases Week: A novel modified jejunum model for endoscopic ultrasonography-guided biliary drainage procedures

Kevin Wood, Jay Budrewicz, Moises Rivera Bermudez, Katrina Hansen. “A novel modified jejunum model for endoscopic ultrasonography-guided biliary drainage procedures.”

Summary: There are a host of disease pathologies within the biliary anatomy that manifest in luminal obstruction and consequential dilation. An Endoscopic Retrograde Cholangiopancreotography (ERCP)-guided biliary drainage procedure is used as the primary approach to restore nominal intraductal pressure and patent bile flow. When encountering structural abnormalities and subsequent failed ERCP-guided cannulation, physicians currently consider two options: endoscopic ultrasonography-guided biliary drainage (EUS-BD) and percutaneous transhepatic biliary drainage (PTBD).

Due to the limitations of current models, a novel approach was required to optimize physician training and device evaluations for EUS-BD procedures. Here we describe a novel porcine model where an isolated, fluid-filled loop of jejunum was targeted in a simulated EUS-BD procedure.

This novel approach successfully overcomes many of the past models’ limitations by minimizing procedural days while increasing the number of possible EUS-BD procedures per animal.

Presented at Digestive Diseases Week 2020, June 1, 2020.