Circulation Research: Arterial ultrastructure influences transport of locally delivered drugs

Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs.

Summary: An incomplete understanding of the transport forces and local tissue structures that modulate drug distribution has hampered local pharmacotherapies in many organ systems. These issues are especially relevant to arteries, where stent-based delivery allows fine control of locally directed drug release.

Circulation Research. 2002 Apr 19. 90(7): 826-832.

April 19, 2002