“Vascular access complications are a significant source of morbidity, especially for interventions such as TAVR that require large bore cannulation,” said Haim Danenberg, M.D., CBSET’s chief scientific advisor. “CBSET’s study demonstrates that MANTA is a safe and reliable large-bore percutaneous closure device.” LEXINGTON, Mass., Dec. 10, 2015 — Scientists at CBSET, a not-for-profit preclinical research […]
Category Archives: Press Releases
Press Release: Data provides new insights into the optimal balance between drug-eluting stent coating material properties and drug elution kinetics
“Drug eluting stents remain a ripe field for continued innovation. Until now, the focus on sustainable drug elution has strictly limited the choice of DES coating materials. Our study results confirm a new paradigm for optimizing coating biocompatibility,” said Rami Tzafriri, PhD, Principal Scientist, CBSET. LEXINGTON, Mass., Oct. 28, 2015 — CBSET, a not-for-profit preclinical […]
Press Release: Primary lesion treatment using Diamondback 360® orbital atherectomy system enhances paclitaxel deposition in calcified peripheral arteries: preclinical data presented at EuroPCR 2015
““This preclinical study could have a significant clinical impact by demonstrating improved drug delivery after modification of calcified lesions,” said Gunnar Tepe, M.D., RoMed Hospital, Rosenheim, Germany. LEXINGTON, Mass., May 20, 2015 — CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education, and advancement of medical technologies, disclosed today that modification of atherosclerotic […]
Press Release: Roadmap for the revitalization of catheter-based renal sympathetic denervation related to clinically meaningful, optimized device design: CBSET to present compelling preclinical evidence at EuroPCR 2015
“Renal denervation, despite recent stumbles, is experiencing a resurgence with next-generation device design. CBSET’s incontrovertible mechanistic data provides the pathway for predicting efficacy and designing more efficacious devices and protocols,” said Peter M. Markham, President and CEO, CBSET. LEXINGTON, Mass., May 18, 2015 — Scientists at CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, […]
Press Release: Variable patient responses to catheter-based renal denervation therapy is explained by local tissue anatomy – suggesting a paradigm for treatment optimization: CBSET data published in Science Translational Medicine
“The combination of both preclinical experiments and computational models is necessary to understand the basis of clinical efficacy: variation in ablation zone geometry caused by diversity in local tissue anatomy,” said Peter M. Markham, President and CEO, CBSET. LEXINGTON, Mass., May 4, 2015 — CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education, and […]
Press Release: New Class of Orthopedic Implants for Intramedullary Biologic Fixation of Fractured Long Bones Validated in Preclinical Models – CBSET, IlluminOss Medical Data Published in Journal of Biomedical Materials Research
IlluminOss System provides minimally invasive approach to replace splints, casts, metal fixator plates and intramedullary rods to stabilize high load-bearing bones* LEXINGTON, Mass., April 10, 2015 — CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education, and advancement of medical technologies, announced today it has published efficacy data showing that percutaneous intramedullary fixation […]
Press Release: Optimal tissue debulking protocol defined for treating in-stent restenosis (ISR) with Boston Scientific’s JETSTREAM® Navitus atherectomy device
CBSET data disclosed at Cardiovascular Research Technologies (CRT) 2015 LEXINGTON, Mass., Feb 25, 2015 — Scientists at CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education, and advancement of medical technologies, announced today that its scientists have defined the optimal tissue debulking protocol for treating in-stent restenosis (ISR) with Boston Scientific’s JETSTREAM® Navitus […]
Press Release: Modification of atherosclerotic plaque with Diamondback360® orbital atherectomy device improves drug uptake in peripheral arteries
Elazer R. Edelman, M.D., Ph.D., presents ex vivo results at Cardiovascular Research Technologies (CRT) 2015 LEXINGTON, Mass., Feb 23, 2015 — Scientists at CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education, and advancement of medical technologies, disclosed today that modification of atherosclerotic plaque with the Diamondback 360® orbital atherectomy device (Cardiovascular Systems, […]
Press Release: Dr. Haim Danenberg joins CBSET as Chief Scientific Adviser
LEXINGTON, Mass., Dec 11, 2014— CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education, and advancement of medical technologies, announced today that it has appointed Haim Danenberg, M.D., as chief scientific adviser, effective immediately. Prof. Danenberg has served as Head of the Cardiovascular Research Center and Director of Interventional Cardiology at the Heart […]
Press Release: Clinical Efficacy of Renal Denervation Therapies is Related to Innervation Patterns, Microanatomical Structures, and Treatment Paradigms: CBSET to Present Further Mechanistic Evidence at ‘TCT 2014’
“Confounding data from recent clinical trials must not deter industry. Sympathetic denervation and neuromodulation techniques still provide an exciting opportunity for the treatment of resistant hypertension and of a variety of other diseases. The current device therapies are still in their infancy, and the rate of technological advancement in this field is accelerating exponentially.Our preclinical […]